Voice over Long Term Evolution (called VoLTE) is always a main service that brings a big benet for mobile operators. However, the deployment of VoLTE is very complex, specially for guaranteeing of Quality of Service (QoS) to meet quality of experience of mobile users. The key purpose of this paper is to present an object, non-intrusive prediction model for VoLTE quality based on LTE-Sim framework and the extended E-model. This combination allows to overcome the lack of the E-model is that how to determine exactly its inputs. Besides, we propose to add the jitter buer as an essential input factor to the E-model. The simulation results show that our proposed model can predict voice quality in LTE network via both the E-model and the Extended E-model. The proposed model does not refer to the original signal, thus, it is very suitable for predicting voice quality in LTE network for many dierent scenarios which are congured in the LTE-Sim framework. The simulation results also show that the eect of jitter buer on user perception is very signicant