In this paper, the evolution of mobile radio network is presented. First of all, the network life cycle is considered. A mathematical modeling of these life periods is developed inside an optimization problem: optimal location of base stations. It is a combinatorial optimization problem. A multi-period model is built on a Concentrator Link approach. Finally, three different multi-period techniques are identified, they are based on Genetic Algorithm (GA) to tackle this problem on the design of micro-cellular networks.