In vivo magnetic resonance spectroscopy for the characterization of colorectal tumors in colitis murine model: initial findings - Archive ouverte HAL Accéder directement au contenu
Communication Dans Un Congrès Année : 2016

In vivo magnetic resonance spectroscopy for the characterization of colorectal tumors in colitis murine model: initial findings

Résumé

Inflammatory bowel diseases (IBD) increase the risk of developing colorectal cancer (CRC) [1]. The abnormal proliferation of cells induces subsurface anatomical and biochemical changes that cannot be early assessed with conventional modalities. Proton magnetic resonance spectroscopy (MRS) has been shown to have clinical value in managing cancers of the brain, breast, prostate, and it may be useful for the diagnosis and monitoring of IBD. Up to now, there have been no reports of the in vivo assessment of colon walls using MRS. In this work, dedicated endorectal coils (EC) [2] which locally improve significantly SNR were used to carry out MRS in small voxel without time penalties or SNR issues for the characterization of colorectal tumors on a mouse model of colitis [3].

Domaines

Imagerie
Fichier non déposé

Dates et versions

hal-01433339 , version 1 (12-01-2017)

Identifiants

  • HAL Id : hal-01433339 , version 1

Citer

Hugo Dorez, Raphaël Sablong, Sophie Gaillard, Driffa Moussata, Hélène Ratiney, et al.. In vivo magnetic resonance spectroscopy for the characterization of colorectal tumors in colitis murine model: initial findings. ESMRMB Annual Scientific Meeting 2016, Sep 2016, Vienna, Austria. ⟨hal-01433339⟩
72 Consultations
0 Téléchargements

Partager

Gmail Facebook X LinkedIn More