Efficient one-pot double Buchwald-Hartwig coupling reaction on 5-phenyl-4- phenylsulfonyl-2,3-dihydrofuran derivatives
Résumé
We report a new and efficient method of conducting a one-pot double Buchwald-Hartwig coupling reaction on 2,3-dihydrofuran derivatives bearing two bromine atoms. This rapid and convenient synthesis allows us to access a great variety of original mixed dicoupled compounds. The strategy appears promising for combinatorial chemistry and pharmacomodulation studies.
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