Impact of Biofield Energy Treated Herbomineral Formulation (The Trivedi Effect®) on Mouse Dendritic and Splenocyte Cells for Modulation of Pro-inflammatory Cytokines - Archive ouverte HAL
Journal Articles International Journal of Immunology Year : 2016

Impact of Biofield Energy Treated Herbomineral Formulation (The Trivedi Effect®) on Mouse Dendritic and Splenocyte Cells for Modulation of Pro-inflammatory Cytokines

Mahendra Kumar Trivedi
Gopal Nayak
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Aileen Carol Lee
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  • PersonId : 996361
Aksana Hancharuk
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  • PersonId : 996362
Carola Marina Sand
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  • PersonId : 996363
Debra Jane Schnitzer
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  • PersonId : 996364
Rudina Thanasi
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  • PersonId : 996365
Eileen Mary Meagher
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  • PersonId : 996366
Faith Ann Pyka
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  • PersonId : 996367
Gary Richard Gerber
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  • PersonId : 996368
Johanna Catharina Stromsnas
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  • PersonId : 996369
Judith Marian Shapiro
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  • PersonId : 996370
Laura Nelson Streicher
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  • PersonId : 996371
Lorraine Marie Hachfeld
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  • PersonId : 996372
Matthew Charles Hornung
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  • PersonId : 996373
Patricia M. Rowe
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  • PersonId : 996374
Sally Jean Henderson
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  • PersonId : 996375
Sheila Maureen Benson
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  • PersonId : 996376

Abstract

The use of herbomineral formulation in the healthcare sector for different chronic diseases is gaining popularity due to its fewer side effects, high safety profile, and cost effectiveness. A new proprietary herbomineral formulation was formulated, consisting of four essential ingredients viz. herbal root extract (ashwagandha), and minerals (zinc, magnesium, and selenium). The study aims to evaluate the in vitro effect of Biofield Energy Healing (The Trivedi Effect®) on the test formulation using murine dendritic (DCs) and splenocyte cells. The herbomineral formulation was divided into two parts; one was represented as control, while the other part was treated with the Biofield Energy Healing Treatment remotely by eighteen renowned Biofield Energy Healers (The Trivedi Effect®) and defined as the Biofield Treated formulation. The effect of the test formulation on these cells were monitored by an estimation of pro-inflammatory cytokines level such as tumor necrosis factor (TNF-α), macrophage inflammatory protein (MIP-1α), and interleukin (IL-1β) in cell culture supernatants at the non-cytotoxic concentrations of the test formulation using MTT assay. The DCs were treated with the Biofield Energy Treated test formulation at different concentrations (i.e. 1.05 to 1052.5 µg/mL) for 24 hours, and the results showed significant (p≤0.001) suppression of TNF-α levels at all the tested concentrations with a maximum percentage decrease by 43.64% at 5.2 µg/mL concentration in the Biofield Treated formulation as compared with the untreated test formulation. Further, the Biofield Treated formulation also demonstrated inhibition of MIP-1α and IL-1β at a concentration range of 0.0000105 to 10.5 µg/mL in LPS stimulated splenocyte cells. There was a significant (p≤0.001) inhibition of MIP-1α (26.52%) and IL-1β (35.28%) in the Biofield Treated test formulation at concentration 0.000105 µg/mL and 0.0000105 µg/mL, respectively in comparison to the untreated test formulation. Overall, these results suggest that the Biofield Energy Healing based herbomineral formulation (The Trivedi Effect®) significantly down-regulated the tested cytokines expression in DCs and splenocyte cells as compared to the untreated formulation. Therefore, the Biofield Healing based formulation might be useful as a better anti-inflammatory product for many chronic and acute inflammatory disease conditions and autoimmune disorders. The Biofield Energy Treatment based formulation can also be effectively applied in cases of organ transplants, stress management and anti-aging by improving overall health.
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hal-01417821 , version 1 (16-12-2016)

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  • HAL Id : hal-01417821 , version 1

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Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Aileen Carol Lee, et al.. Impact of Biofield Energy Treated Herbomineral Formulation (The Trivedi Effect®) on Mouse Dendritic and Splenocyte Cells for Modulation of Pro-inflammatory Cytokines. International Journal of Immunology, 2016, 4 (5), pp.35-45. ⟨hal-01417821⟩
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