Synthesis of Allenes Bearing Phosphine Oxide Groups and Investigation of Their Reactivity toward Gold Complexes
Résumé
A collection of phosphine oxide allenes has been prepared. Their coordination to gold(I) has been studied giving new coordination complexes when a pendant pyridine moiety was present. Alternatively, their gold(I)-catalyzed cycloisomerization has proven to be quite efficient. An almost complete axial-to-central chirality transfer in the cyclization process was observed, opening the potential access to valuable enantiopure phosphorus derivatives.