In this paper, we present a practical case of the multiobjective knapsack problem which concerns the elaboration of the optimal action plan in the social and medico-social sector. We provide a description and a formal model of the problem as well as some preliminary computational results. We perform an empirical analysis of the behavior of three metaheuristic approaches: a fast and elitist multiobjective genetic algorithm (NSGA-II), a Pareto Local Search (PLS) algorithm and an Indicator-Based Multi-Objective Local Search (IBMOLS).