In this review-essay, Giuseppe Longo outlines some important reasons for reading Sergio Chibbaro, Lamberto Rondoni, and Angelo Vulpiani’s Reductionism, Emergence and Levels of Reality: The Importance of Being Borderline, and reflects on the damage done by reductionist models of, and in, scienceThis book arrives at a most suitable time. A critique of reductionism originating from within physics may be the most effective way to halt and repair the damage caused by the misuse of physicalist reductionism in biology and in other sciences. I strongly recommend this book to all scientifically educated persons and, in particular, to biologists, and physicists studying biological phenomena. The authors, three working physicists, address the complex theoretical dynamics that connect theories and knowledge levels within physics, a science where, I would dare to say, ‘reduction’ never applies....