Synthesis of new 6-halogeno-imidazo[1,2-a]pyridines by SRN1 reactions - Archive ouverte HAL
Article Dans Une Revue ARKIVOC - Online Journal of Organic Chemistry Année : 2003

Synthesis of new 6-halogeno-imidazo[1,2-a]pyridines by SRN1 reactions

Résumé

New 2-chloromethyl-6-halogeno-imidazo[1,2-a]pyridines and 2-chloromethyl-6-halogeno-3-nitroimidazo[1,2-a]pyridines were prepared and reacted under experimental conditions of S RN 1 reactions with different sulfur and carbon centered nucleophiles to give new 6-halogeno-2-substituted-imidazo[1,2-a]pyridines and 6-halogeno-3-nitro-2-substituted-imidazo[1,2-a] pyridines in good yields. Only the chloromethyl group was found to be reactive under these experimental conditions.
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Dates et versions

hal-01358995 , version 1 (05-09-2016)

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Maxime D. Crozet, Caroline Castera, Mustapha Kaafarani, Michel P. Crozet, Patrice Vanelle. Synthesis of new 6-halogeno-imidazo[1,2-a]pyridines by SRN1 reactions. ARKIVOC - Online Journal of Organic Chemistry, 2003, ARKIVOC, 2003 (x), pp.273-282. ⟨10.3998/ark.5550190.0004.a26⟩. ⟨hal-01358995⟩

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