Interaction between olfaction and food intake: metabolic state drives changes in the astroglial deployment within the olfactory bulb glomeruli in rats
Résumé
Olfaction participates in the elaboration of the hedonic value of foods, food choice and the regulation of food intake. Reciprocally, the detection of food odors is influenced by metabolic state and thereby contributes
to the initiation and termination of eating behavior. Fasting increases olfactory performances, notably by increasing neuronal activation in the olfactory bulb (OB) (Prud’homme et al, 2009), the first integration site of
olfactory signals towards the central nervous system. Within the OB glomeruli, glutamatergic synapses between olfactory sensory neurons and mitral cells are regulated by periglomerular neurons and astrocytes.
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