Selective manipulation of microscopic particles with swirling Rayleigh waves
Résumé
Acoustical vortices offer tremendous perspective for dexterous contactless manipulation. In order to fulfill their potential of selective though label-free biocompatible tweezers, they must nonetheless become flat, smaller and easily integrable with disposable substrates. In this letter, we synthesize acoustic vortices using an integrated transducer by solving an inverse problem. We then capture and pattern tens of 30 µm particles on disposable substrates. Finally, we compare the forces applied by our vortices to theoretical calculations. This technology offers numerous prospects for micro-fabrication and cell-printing. High precision contactless manipulation offers tremendous perspectives for biophysical investigations and breakthroughs such as biological cell printing. A large span of methods using magnetic [1, 2], optical [3, 4], electrical [5] and acoustical forces [6, 7], and their combination [8] have been proposed. Among these techniques, acoustic tweezers stand out for cell manipulation applications as they combine high bio-compatibility [9], label-free manipulation [10], relatively low cost and disposable parts for minimized sample contamination [11]. One approach to capture individual particles relies on an ultra-sonic beam in the Mie scattering regime (particle size >> wavelength) [12]. Herein, very high frequencies (between 100 MHz and 1 GHz) are required to achieve selective manipulation, resulting in a deleterious heating of the manipulated sample [13] and the need of high-end electronics .
Origine | Fichiers produits par l'(les) auteur(s) |
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