We introduce Radical Interactionism (RI), which extends Franklin et al.’s (2013) Cognitive Cycles as Cognitive Atoms (CCCA) proposal in their discussion on conceptual commitments in cognitive models. Similar to the CCCA commitment, the RI commitment acknowledges the indivisibility of the perception-action cycle. However, it also reifies the perception-action cycle as sensorimotor interaction and uses it to replace the traditional notions of observation and action. This complies with constructivist epistemology, which suggests that knowledge of reality is constructed from regularities observed in sensorimotor experience. We use the LIDA cognitive architecture as an example to examine the implications of RI on cognitive models. We argue that RI permits self-programming and constitutive autonomy, which have been acknowledged as desirable cognitive capabilities in artificial agents.