In this study, an approach to re-planning the multi-stage supply chain (SC) subject to disruptions is developed. We analyze seven proactive SC structures, compute recovery policies to re-direct material flows in the case of two disruption scenarios, and assess the performance impact for both service level and costs with the help of a SC (re)planning model containing elements of system dynamics and linear programming. In the result, an explicit connection of performance impact assessment and SC plan reconfiguration issues with consideration of the duration of disruptions and the costs of recovery has been achieved.