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            <title xml:lang="en">A Web interface generator for molecular biology programs in Unix</title>
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                <title xml:lang="en">A Web interface generator for molecular biology programs in Unix</title>
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                <title level="j">Bioinformatics</title>
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                <term xml:lang="en"> scripting</term>
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                <term xml:lang="en"> sequence analysis</term>
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              <p>Motivation: Almost all users encounter problems using sequence analysis programs. Not only are they difficult to learn because of the parameters, syntax and semantic , but many are different. That is why we have developed a Web interface generator for more than 150 molecular biology command-line driven programs, including: phy-logeny, gene prediction, alignment, RNA, DNA and protein analysis, motif discovery, structure analysis and database searching programs. The generator uses XML as a high-level description language of the legacy software parameters. Its aim is to provide users with the equivalent of a basic Unix environment, with program combination, cus-tomization and basic scripting through macro registration. Results: The program has been used for three years by about 15 000 users throughout the world; it has recently been installed on other sites and evaluated as a standard user interface for EMBOSS programs.  </p>
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