Information Systems are viewed as a set of services creating a workflow of information directed to specific groups and members. This allows individuals to share ideas and their talents with other members. In such manner , tasks can be carried out both efficiently and effectively. Due to the nature of Information Systems that revolves around creating information useful to users , and in some higher forms of Information Systems creating knowledge , management of information and / or knowledge is part of their functionalities. In this paper we aim to study the placement of Information Systems as part of a System of Systems (SoS) , as these large systems poses significant technical improvement in terms of information interoperability that overcomes conceptual and technical barriers. Therefore , we move towards defining and modeling System of Information Systems (SoIS). This paper discovers what is currently known about Information Systems and Systems of Systems , and proceeds towards suggesting an architecture of a System of Information Systems that integrates several Information Systems and allows information to be transferred at ease between those different components .