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<< /S /GoTo /D (Doc-Start) >>
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4 0 obj
(Summary)
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<< /S /GoTo /D (Doc-Start) >>
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7 0 obj
(Introduction)
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<< /S /GoTo /D (section*.1) >>
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(Molecular Diagnosis of ALL)
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<< /S /GoTo /D (section*.1) >>
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(Repertoire Sequencing \(Rep-Seq\) for ALL diagnosis and MRD)
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<< /S /GoTo /D (section*.1) >>
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(Challenges)
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<< /S /GoTo /D (section*.1) >>
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(Repertoire Sequencing \(Rep-Seq\) analysis software)
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<< /S /GoTo /D (section*.1) >>
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(Contents)
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<< /S /GoTo /D (section*.1) >>
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(Patients and methods)
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<< /S /GoTo /D (section*.2) >>
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(Patient selection)
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<< /S /GoTo /D (section*.2) >>
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(DNA extraction and amplification)
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<< /S /GoTo /D (section*.2) >>
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(Preparation of libraries)
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<< /S /GoTo /D (section*.2) >>
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(Emulsion PCR, enrichment and High-throughput sequencing)
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<< /S /GoTo /D (section*.2) >>
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(Bioinformatics analysis and visualisation)
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<< /S /GoTo /D (section*.2) >>
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(Results)
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46 0 obj
<< /S /GoTo /D (table.1) >>
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(Identification of the main clones)
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<< /S /GoTo /D (figure.1) >>
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53 0 obj
(Sequencing)
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54 0 obj
<< /S /GoTo /D (table.2) >>
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(Reproducibility of PCR and HTS)
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<< /S /GoTo /D (figure.2) >>
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(Handling sequencing errors)
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<< /S /GoTo /D (figure.2) >>
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64 0 obj
(Comparison between Vidjil, IMGT/V-QUEST and IgBlast on V\(D\)J designation)
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<< /S /GoTo /D (table.3) >>
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(Discussion)
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<< /S /GoTo /D (section*.3) >>
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(Quantity of DNA)
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<< /S /GoTo /D (section*.3) >>
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(Sequencing quality)
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<< /S /GoTo /D (section*.3) >>
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(Fragment length)
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<< /S /GoTo /D (section*.3) >>
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(V\(D\)J designation)
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<< /S /GoTo /D (section*.3) >>
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(Reproducibility and contaminations)
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<< /S /GoTo /D (section*.3) >>
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(Bioinformatics analysis and visualisation)
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<< /S /GoTo /D (section*.3) >>
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(Feasibility in haematological lab)
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<< /S /GoTo /D (section*.3) >>
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93 0 obj
(Conclusion and perspectives)
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<< /S /GoTo /D [95 0 R /Fit] >>
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