Evaluation of a new transperineal ultrasound probe for inter-fraction image-guidance for definitive and post-operative prostate cancer radiotherapy - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Physica Medica European Journal of Medical Physics Année : 2016

Evaluation of a new transperineal ultrasound probe for inter-fraction image-guidance for definitive and post-operative prostate cancer radiotherapy

Résumé

PurposeThe aim of this study was to evaluate a new system based on transperineal ultrasound (TP-US) acquisitions for prostate and post-prostatectomy pre-treatment positioning by comparing this device to cone-beam computed tomography (CBCT).MethodsThe differences between CBCT/CT and TP-US/TP-US registrations were analyzed on 427 and 453 sessions for 13 prostate and 14 post-prostatectomy patients, respectively. The inter-operator variability (IOV) of the registration process, and the impact and variability of the probe pressure were also evaluated.ResultsCBCT and TP-US shift agreements at ± 5 mm were 76.6%, 95.1%, 96.3% and 90.3%, 85.0%, 97.6% in anterior-posterior, superior-inferior and left-right directions, for prostate and post-prostatectomy patients, respectively. IOV values were similar between the 2 modalities. Displacements above 5 mm due to strong pressures were observed on both localizations, but such pressures were rarely reproduced during treatment courses.ConclusionsHigh concordance between CBCT/CT and TP-US/TP-US localization of prostates or prostatic beds was found in this study. TP-US based prepositioning is a feasible method to ensure accurate treatment delivery, and represents an attractive alternative to invasive and/or irradiating imaging modalities.

Domaines

Cancer Imagerie
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Dates et versions

hal-01273174 , version 1 (12-02-2016)

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Marie Fargier-Voiron, Benoît Presles, Pascal Pommier, Alexandre Munoz, Simon Rit, et al.. Evaluation of a new transperineal ultrasound probe for inter-fraction image-guidance for definitive and post-operative prostate cancer radiotherapy. Physica Medica European Journal of Medical Physics, 2016, 32 (3), pp.499-505. ⟨10.1016/j.ejmp.2016.01.481⟩. ⟨hal-01273174⟩
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