The understanding of spray combustion processes is of primary importance, as it is encountered in a wide range of industrial applications. In the present work, mesoscale-resolved simulations of a 3D turbulent counterflow spray configuration are conducted. Primary focus is on examining the effect of the coupling between turbulence, evap- oration, mixing, and combustion. By considering different initial droplet diameters and through comparisons with turbulent and laminar configurations at the same operating condition, it is shown that preferential concentration can lead to conditions of locally high mixture-fraction composition. In addition, local variability in strain rate and droplet diameter introduces a bifurcation of the spray flame. This bifurcation consists of spray flame structures exhibiting single-reaction or double-reaction structures. It is shown that this bimodal behavior is linked to the existence of a hysteresis in the laminar spray flame structure for droplet diameter variations, as well as the occurrence of a bifur- cation for strain rate variations. These results have direct implications for flamelet-based tabulation methods, since identifying the appropriate flamelet structure in turbulent spray flames would require informations about boundary conditions and the flamelet history.