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Article Dans Une Revue Journal of Agricultural and Food Chemistry Année : 2014

Impact of Wheat aleurone structure on metabolic disorders caused by a high-fat diet in Mice

Résumé

The present study investigated the potential of native and structurally modified wheat aleurone, by dry-grinding or enzymatic treatments, to counteract metabolic disorders in mice with diet-induced obesity (DIO). C57BL6/J mice were first fed ad libitum with a high-fat diet for 9 weeks to induce obesity, after which the native or treated aleurone fractions were added (13% (w/w)) in the high-fat diets for an additional 8 weeks. The effects of the aleurone-enriched diets were evaluated by assessing body weight gain, adiposity, fasting blood glucose, plasma insulin and leptin, and anti-inflammatory and oxidative stress markers. Enrichment of the diet with native or finely ground aleurone did not improve any parameter analyzed; finely ground aleurone even slightly increased (p = 0.03) body weight gain. Enrichment of the diet with enzymatically treated aleurone only had a tendency toward lower body weight gain, visceral adipose tissue accumulation, fasting plasma insulin, and leptin levels.
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Dates et versions

hal-01268932 , version 1 (04-02-2016)

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Natalia Rosa, Jenna Pekkinen, Karla Zavala, Gilles Fouret, Ayhan Korkmaz, et al.. Impact of Wheat aleurone structure on metabolic disorders caused by a high-fat diet in Mice. Journal of Agricultural and Food Chemistry, 2014, 62 (41), pp.10101-10109. ⟨10.1021/jf503314a⟩. ⟨hal-01268932⟩
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