A general and efficient method to access tetracyclic spirooxindole derivatives. - Archive ouverte HAL Access content directly
Journal Articles European Journal of Organic Chemistry Year : 2015

A general and efficient method to access tetracyclic spirooxindole derivatives.

Abstract

An efficient, simple, and convenient synthetic procedure for the synthesis of tetracyclic spirooxindole derivatives, starting from N-protected isatins and 2-fluoropyridine, was successfully developed. It enables the facile formation of a new class of spirooxindoles in which the oxindole core is fused with various heterocycles at the C-3 position.

Dates and versions

hal-01212463 , version 1 (06-10-2015)

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Abderrahman El Bouakher, Stéphane Massip, Christian Jarry, Yves Troin, Isabelle Abrunhosa-Thomas, et al.. A general and efficient method to access tetracyclic spirooxindole derivatives.. European Journal of Organic Chemistry, 2015, pp.556-559. ⟨10.1002/ejoc.201403292⟩. ⟨hal-01212463⟩
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