Assessment of the Probiotic Potential of a Dairy Product Fermented by [i]Propionibacterium freudenreichii[/i] in Piglets - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Agricultural and Food Chemistry Année : 2012

Assessment of the Probiotic Potential of a Dairy Product Fermented by [i]Propionibacterium freudenreichii[/i] in Piglets

Résumé

Dairy propionibacteria, including Propionibacterium freudenreichii, display promising probiotic properties, including immunomodulation. These properties are highly strain-dependent and rarely studied in a fermented dairy product. We screened 10 strains, grown in a newly developed fermented milk ultrafiltrate, for immunomodulatory properties in vitro. The most anti-inflammatory strain, P. freudenreichii BIA129, was further tested on piglets. P. freudenreichii-fermented productimproved food intake and growth of piglets. Colonic mucosa explants of treated pigs secreted less interleukin 8 (−25%, P < 0.05) and tumor necrosis factor α (−20%, P < 0.05), either in basal conditions or after a lipopolysaccharide challenge. By contrast, the gut structure, barrier function (measured ex vivo in Ussing chambers), microbial diversity (assessed by 16S rRNA pyrosequencing), and colonic short-chain fatty acid content were unchanged, assuming maintenance of normal intestinal physiology. In conclusion, this work confirms in vivo probiotic properties of dairy propionibacteria-fermented products, which are promising for the prevention or healing of inflammatory bowel diseases.
Fichier non déposé

Dates et versions

hal-01209320 , version 1 (02-10-2015)

Identifiants

Citer

Fabien Cousin, Benoît Foligné, Stéphanie-Marie Deutsch, Sébastien Massart, Sandrine Parayre-Breton, et al.. Assessment of the Probiotic Potential of a Dairy Product Fermented by [i]Propionibacterium freudenreichii[/i] in Piglets. Journal of Agricultural and Food Chemistry, 2012, 60, pp.7917-7927. ⟨10.1021/jf302245m⟩. ⟨hal-01209320⟩
97 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More