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Communication Dans Un Congrès Année : 2015

2D Correlated MRS as a quantitative method to asses liver fatty acid composition of ob/ob mouse

Résumé

Magnetic Resonance Spectroscopy (MRS) is a well suited method for in vivo characterization of lipid content. However, due to short T2relaxation time and B0 field inhomogeneity, classical methods such as STEAM/PRESS MRS, with clinical or medium preclinical B0 field (B0<9.4T), can be limited by their spectral resolution, leading to quantification ambiguity and thus lipid composition assessment error. The aim of this work is to demonstrate the use of a 2D MRS method called L-COSY and its quantification by a proper dedicated time domain quantification procedure using prior knowledge on triglyceride chemical groups and their connectivity.

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Dates et versions

hal-01208316 , version 1 (02-10-2015)

Identifiants

  • HAL Id : hal-01208316 , version 1

Citer

D. Martel, J.-B. Langlois, Denis Friboulet, O. Beuf, H. Ratiney. 2D Correlated MRS as a quantitative method to asses liver fatty acid composition of ob/ob mouse. ISMRM 23rd Annual Meeting & Exhibition, May 2015, Toronto, Canada. ⟨hal-01208316⟩
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