On the structural, mechanical, and biodegradation properties of HA/β-TCP robocast scaffolds - Archive ouverte HAL
Article Dans Une Revue Journal of Biomedical Materials Research Année : 2013

On the structural, mechanical, and biodegradation properties of HA/β-TCP robocast scaffolds

Résumé

Hydroxyapatite/β-tricalcium phosphate (HA/β-TCP) composite scaffolds have shown great potential for bone-tissue engineering applications. In this work, ceramic scaffold with different HA/β-TCP compositions (pure HA, 60HA/40β-TCP, and 20HA/80β-TCP) were fabricated by a robotic-assisted deposition (robocasting) technique using water-based hydrogel inks. A systematic study was conducted to investigate the porosity, mechanical property, and degradation of the scaffolds. Our results indicate that, at a similar volume porosity, the mechanical strength of the sintered scaffolds increased with the decreasing rod diameter. The compressive strength of the fabricated scaffolds (porosity ≈ 25–80 vol %) varied between ∼3 and ∼50 MPa, a value equal or higher than that of human cancellous bone (2–12 MPa). Although there was a slight increase of Ca and P ions in water after 5 month, no noticeable degradation of the scaffolds in SBF or water was observed. Our findings from this work indicate that composite calcium phosphate scaffolds with customer-designed chemistry and architecture may be fabricated by a robotic-assisted deposition method.

Domaines

Matériaux
Fichier principal
Vignette du fichier
paper.v4.pdf (873.23 Ko) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-01196354 , version 1 (05-01-2017)

Identifiants

Citer

Manuel Houmard, Qiang Fu, Martin Genet, Eduardo Saiz, Antoni P. Tomsia. On the structural, mechanical, and biodegradation properties of HA/β-TCP robocast scaffolds. Journal of Biomedical Materials Research, 2013, 101 (7), pp.9. ⟨10.1002/jbm.b.32935⟩. ⟨hal-01196354⟩
38 Consultations
390 Téléchargements

Altmetric

Partager

More