Influencia de la dieta sobre las citoquinas antiinflamatorias en la enfermedad de Crohn
Résumé
[b]Background:[/b] Crohn’s disease is a digestive illness that causes inflammation in genetically susceptible pa- tients. Given the relationship between Crohn’s disease, microbiota and diet, theintake of functional foods to promote the modification of microbiota profile and /or the synthesis of antiinflammatory cytokines and thus decrease the effects of inflammation has been evaluated, under de assumption that a proper diet could be used as a means to improve the health of this population group. [br/]
[b]Methods:[/b] An extensive research in scientific publications was performed in the following electronic spe- cialized databases: PubMed central (PMC)-NBCI, Elsevier Journal, Scielo Spain, Scirus, and Science Direct.[br/]
[b]Results:[/b] Several studies have shown that probiotics are not as effective as expected because of intestinal bacteria population in compromised. However, it has been observed that enteral nutrition and the adminis- tration of certain nutraceuticals components such as fish bioactive peptides, colostrum and bovine serum, as well as Boswella serrata, calcium, curcuma and multivitamins can be the first therapy in Crohn’s disease since they induce mucosal reparation and reduce inflammation. [br/]
[b]Conclusions:[/b] More clinical studies in humans are required to clarify the possible effect of functional foods on the control and development of Crohn’s disease.