Cyclodextrin Polyrotaxanes as a Highly Modular Platform for the Development of Imaging Agents
Résumé
Selectively functionalized cyclodextrins with a bodipy fluorescent tag or Gd3+ complex were synthetized and threaded onto a polyammonium chain to form polyrotaxanes. This modular supramolecular assembly makes an ideal platform for bimodal (fluorescent and MRI) imaging applications.