Synthesis and biology of cyclic imine toxins, an emerging class of potent, globally distributed marine toxins. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue (Article De Synthèse) Natural Product Reports Année : 2015

Synthesis and biology of cyclic imine toxins, an emerging class of potent, globally distributed marine toxins.

Résumé

From a small group of exotic compounds isolated only two decades ago, Cyclic Imine (CI) toxins have become a major class of marine toxins with global distribution. Their distinct chemical structure, biological mechanism of action, and intricate chemistry ensures that CI toxins will continue to be the subject of fascinating fundamental studies in the broad fields of chemistry, chemical biology, and toxicology. The worldwide occurrence of potent CI toxins in marine environments, their accumulation in shellfish, and chemical stability are important considerations in assessing risk factors for human health. This review article aims to provide an account of chemistry, biology, and toxicology of CI toxins from their discovery to the present day.
Fichier principal
Vignette du fichier
nihms637436.pdf (2.96 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-01178830 , version 1 (21-02-2024)

Identifiants

Citer

Craig E Stivala, Evelyne Benoit, Rómulo Aráoz, Denis Servent, Alexei Novikov, et al.. Synthesis and biology of cyclic imine toxins, an emerging class of potent, globally distributed marine toxins.. Natural Product Reports, 2015, 32 (3), pp.411-35. ⟨10.1039/c4np00089g⟩. ⟨hal-01178830⟩
253 Consultations
1 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More