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Article Dans Une Revue IEEE Transactions on Dielectrics and Electrical Insulation Année : 2015

Influence of the architecture on the molecular mobility of synthetic fragments inspired from human tropoelastin

Résumé

This work deals with the vibrational, thermal and dielectric characterization of a synthetic peptide (S4) released during the proteolysis of human tropoelastin. This peptide was shown to form amyloid-like fibers implied in neurodegenerative pathologies. The comparison between the linear peptides and the associated amyloidlike fibers evidences the strong influence of the secondary structures on the physical structure and chain dynamics of these polypeptides.
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hal-01162785 , version 1 (11-06-2015)

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Valérie Samouillan, Jany Dandurand, Nicolas Causse, Colette Lacabanne, Brigida Bochicchio, et al.. Influence of the architecture on the molecular mobility of synthetic fragments inspired from human tropoelastin. IEEE Transactions on Dielectrics and Electrical Insulation, 2015, vol. 22 (n° 3), pp. 1427-1433. ⟨10.1109/TDEI.2015.7116333⟩. ⟨hal-01162785⟩
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