A Synthetic Route to 3-(Heteroaryl)-7-hydroxycoumarins Designed for Biosensing Applications
Résumé
A condensation reaction between 7‐acetoxy‐3‐formylcoumarin and various C‐ and/or N‐monosubstituted ortho‐phenylendiamine derivatives has led to a new class of 3‐(heteroaryl)‐7‐hydroxycoumarins meeting the requirements for biosensing applications (bioconjugation ability, water solubility, and high “fluorogenic” reactivity).