From the past decades the monitoring of civil engineering structure became a major field of research anddevelopment process in the domains of modelling and integrated instrumentation. This increasing of interest canbe attributed in part to the need of controlling the aging of such structures and on the other hand to the need tooptimize maintenance costs. From this standpoint the project Cloud2SM (Cloud architecture design for StructuralMonitoring with in-line Sensors and Models tasking), has been launched to develop a robust information systemable to assess the long term monitoring of civil engineering structures as well as interfacing various sensors anddata. The specificity of such architecture is to be based on the notion of data processing through physical orstatistical models. Thus the data processing, whether material or mathematical, can be seen here as a resource ofthe main architecture.