We address the problem of content replication in large distributed content delivery networks, composed of a data center assisted by many small servers with limited capabilities and located at the edge of the network. The objective is to optimize the placement of contents on the servers to offload as much as possible the data center. We model the system constituted by the small servers as a loss network, each loss corresponding to a request to the data center. Based on large system / storage behavior, we obtain an asymptotic formula for the optimal replication of contents and propose adaptive schemes related to those encountered in cache networks but reacting here to loss events, and faster algorithms generating virtual events at higher rate while keeping the same target replication. We show through simulations that our adaptive schemes outperform significantly standard replication strategies both in terms of loss rates and adaptation speed.