Chemical composition, antimicrobial activity and chromosome number of Globularia alipum from Algeria.
Résumé
The chemical composition of essential oil, isolated from Globularia alipum by hydrodistillation, was analysed by GC and GC/MS. A total 39 compounds representing 98.9% of the oil were identified in Boutaleb population, and 89.7% of the total oil in Khenchela population. The essential oil of G. alipum is Characterized by a high rate of hexadecanoic acid (palmetic acid), 14.64% for Boutaleb population and a rate of 29.52% for Khenchela population. Other major compounds are present in the essential oils of G. alipum, the phytol isomer (9.9-5.43%); (Z.Z)-6,9-cis-3,4-epoxy-nonadecadi (8.27-5.45%); 1,2-Benzene dicarboxylic acid-bis (4.68-6.09%); L-linalool (3.49-3.83%) and the heptadecane (2.29-3.28%) respectively for Boutaleb and Khenchela populations. To test the antibacterial activity of essential oil of G. alipum, eleven bacteria are used in this study. The oil showed a significant effect against Gram-negative bacteria, and modest antibacterial activity against Gram-positive bacteria. The populations of G. alipum studied showed a diploid chromosome number with 2n = 2x = 16, and a basic chromosome number x = 8.