Journal Articles Bioinformatics Year : 2015

tmle.npvi: targeted, integrative search of associations between DNA copy number and gene expression, accounting for DNA methylation: Fig. 1.

Antoine Chambaz
Modélisation aléatoire de Paris X
Pierre Neuvial
Laboratoire de Mathématiques et Modélisation d'Evry
CV

Abstract

We describe the implementation of the method introduced by Chambaz et al. (2012). We also demonstrate its genome-wide application to the integrative search of new regions with strong association between DNA copy number and gene expression accounting for DNA methylation in breast cancers. Availability and implementation: An open-source R package tmle.npvi is available from CRAN (http://cran.r-project.org/). Contact: pierre.neuvial@genopole.cnrs.fr

Keywords

HUMAN BREAST-TUMORS

Domains

Statistics [math.ST] Bioinformatics [q-bio.QM]
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https://hal.science/hal-01113680

Submitted on : Friday, February 6, 2015-10:48:31 AM

Last modification on : Saturday, April 27, 2024-3:16:27 AM

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hal-01113680 , version 1 (06-02-2015)

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Antoine Chambaz, Pierre Neuvial. tmle.npvi: targeted, integrative search of associations between DNA copy number and gene expression, accounting for DNA methylation: Fig. 1.. Bioinformatics, 2015, 31 (18), pp.3054-6. ⟨10.1093/bioinformatics/btv320⟩. ⟨hal-01113680⟩

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