Motivated by the analysis of social networks, we study a model of random networks that has both a given degree distribution and a tunable clustering coefficient. We consider two types of growth process on these graphs that model the spread of new ideas, technologies, viruses, or worms: the diffusion model and the symmetric threshold model. For both models, we characterize conditions under which global cascades are possible and compute their size explicitly, as a function of the degree distribution and the clustering coefficient. Our results are applied to regular or power-law graphs with exponential cutoff and shed new light on the impact of clustering.