Synthesis of peptide-grafted comb polypeptides via polymerisation of NCA-peptides.
Résumé
A straightforward synthesis of comb-polypeptides of repeated peptide sequences was developed. These polypeptides were obtained by ROP of defined NCA without any post-polymerization grafting. The key to this strategy relies on the preparation of pure NCA bearing a peptide sequence on its side chain, by an original solid supported methodology.
Domaines
Chimie organique| Origine | Fichiers produits par l'(les) auteur(s) |
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