An analytic solution on fully developed forced convection, in parallel plate porous micro-channels is accomplished in Local Thermal Non-Equilibrium (LTNE) condition. The analysis is realized in steady state regime for rarefied gaseous slip flows between two parallel plates with assigned heat flux. The Darcy-Brinkman model is considered in the momentum equation and two energy equations are used to evaluate solid and fluid temperatures. The entropy generation analysis is performed and the total entropy generation number is evaluated as a function of the different dimensionless parameters. The effect of tangential momentum and thermal accommodation coefficients are examined. Results are reported in terms of average Nusselt numbers, dimensionless temperature profiles and total entropy generation number as a function of Biot number (Bi), effective thermal conductive ratio (k), Darcy number (Da), accommodation coefficients (tangential momentum and thermal) and Knudsen number. Results show that heat transfer increases as Bi increases and reaches asymptotic values. Different trends are observed with respect to tangential momentum accommodation coefficient for assigned thermal accommodation. Total entropy generation number as a function of Da_0.5 presents minimum values with respect to Bi, accommodation coefficients and Brinkman number.