Industrial motion control of dual–drive gantry stages is usually performed by position controllers acting independently on each actuator. This approach neglects the unbalance and the mechanical coupling between actuators, leading to poor positioning performances. To overcome this drawback, a model–based decoupling control is proposed. Initially, a dynamic model of the gantry stage is proposed. Once identified and validated,such model is written in terms of a decoupling basis. Then, by model inversion, a feedback feedforward decoupling control is presented. Experimental results show that, in comparison to the independent axis control approach, the proposed solution leads to improved motion control.