Abstract--In this paper, we present a distributed and autonomic mediation framework named Cilia, dedicated to complex physical environments like manufacturing plants, electrical infrastructures or smart buildings. We detail a motivating example in these fields and we explain how autonomic features are absolutely necessary in domains characterized by important environmental dynamism and by evolving needs of decision-makers. We also present in detail the main principles of Cilia, including its autonomic abilities. We believe that these autonomic behaviors are necessary to deal with Big Data in industrial contexts. Cilia has been validated in collaborative projects with Orange and Schneider Electric.