A multidisciplinary approach integrating self-potential, soil temperature, heat flux, CO2 efflux and gravity gradiometry signals was used to investigate a relatively small fissure-related hydrothermal system near the summit of Mt. Etna volcano (Italy). Measurements were performed through two different surveys carried out at the beginning and at the end of July 2009, right after the end of the long-lived 2008-2009 flank eruption and in coincidence with an increase in diffuse flank degassing related to a reactivation of the volcano, leading to the opening of a new summit vent (NSEC). The main goal was to use a multidisciplinary approach to the detection of hidden fractures in an area of evident near-surface hydrothermal activity. Despite the different methodologies used and the different geometry of the sampling grid between the surveys, all parameters concurred in confirming that the study area is crossed by faults related with the main fracture systems of the south flank of the volcano, where a continuous hydrothermal circulation is established. Results also highlighted that hydrothermal activity in this area changed both in space and in time. These changes were a clear response to variations in the magmatic system, notably to migration of magma at various depth within the main feeder system of the volcano. The results suggest that this specific area, initially chosen as the optimal test-site for the proposed approach, can be useful in order to get information on the potential reactivation of the summit craters of Mt. Etna.