We present in the paper a system that integrates all hardware and software to extract information from 3D images of skin. It is composed of a lighting equipment and stereoscopic cameras, a camera calibration algorithm that uses evolutionary principles, virtual reality equipment to visualize the images and interact with them in 3D, a set of interactive features to annotate images, to create links between them and to build a 3D hypermedia. We present an experimental study and an application of our tool on faces skin.