Convenient preparation of α-bromo-α-fluoro-β-hydroxy esters building blocks from aldehydes, ketones and lactones - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Tetrahedron Letters Année : 2011

Convenient preparation of α-bromo-α-fluoro-β-hydroxy esters building blocks from aldehydes, ketones and lactones

Résumé

A Reformatsky-type addition of ethyl dibromofluoroacetate associated with diethylzinc to various carbonyl compounds is described. Aldehydes, ketones and lactones were converted into the corresponding α-bromo-α-fluoro-β-hydroxyesters in good yields.

Domaines

Chimie organique

Dates et versions

hal-01017744 , version 1 (03-07-2014)

Identifiants

Citer

Ludivine Zoute, Gérald Lemonnier, Tanh-Mai Nguyen, Jean-Charles Quirion, Philippe Jubault. Convenient preparation of α-bromo-α-fluoro-β-hydroxy esters building blocks from aldehydes, ketones and lactones. Tetrahedron Letters, 2011, 52 (19), pp.2473-2475. ⟨10.1016/j.tetlet.2011.03.014⟩. ⟨hal-01017744⟩
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