Synthesis of substituted diazino[c]quinolin-5(6H)-ones, diazino[c]isoquinolin-6(5H)-ones, diazino[c]naphthyridin-6(5H)-ones and diazino[c]naphthyridin-5(6H)-ones - Archive ouverte HAL
Article Dans Une Revue Tetrahedron Année : 2013

Synthesis of substituted diazino[c]quinolin-5(6H)-ones, diazino[c]isoquinolin-6(5H)-ones, diazino[c]naphthyridin-6(5H)-ones and diazino[c]naphthyridin-5(6H)-ones

Résumé

Substituted diazino[c]quinolin-5(6H)-ones and -isoquinolin-6(5H)-ones, diazino[c]naphthyridin-6(5H)- and -5(6H)-ones were obtained using two synthetic routes: one-pot cross-coupling/cyclization and two-step cross-coupling/KOH-mediated anionic ring closure. The two strategies gave yields in the same order of magnitude and their choice depends on the availability of the starting material.

Domaines

Chimie organique

Dates et versions

hal-01015241 , version 1 (26-06-2014)

Identifiants

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Nathalie Fresneau, Thomas Cailly, Frédéric Fabis, J.-P. Bouillon. Synthesis of substituted diazino[c]quinolin-5(6H)-ones, diazino[c]isoquinolin-6(5H)-ones, diazino[c]naphthyridin-6(5H)-ones and diazino[c]naphthyridin-5(6H)-ones. Tetrahedron, 2013, pp.5393-5400. ⟨10.1016/j.tet.2013.04.104⟩. ⟨hal-01015241⟩
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