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Article Dans Une Revue Organic Letters Année : 2013

Universal dark quencher based on "clicked" spectrally distinct azo dyes.

Résumé

The first synthesis of an heterotrifunctional molecular scaffold derived from the popular DABCYL azo dye quencher has been achieved. The sequential derviatization of this trivalent azobenzene derivative with two other nonfluorescent azo dyes (Black Hole Quencher BHQ-1 and BHQ-3) and through effective reactions from the "bioconjugation chemistry" repertoire has led to an universal dark quencher (UDQ). This "clicked" poly azo dye is able to turn off an array of fluorophores covering the UV/NIR (300-750 nm) spectral range.

Domaines

Chimie organique
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Dates et versions

hal-00996556 , version 1 (26-05-2014)

Identifiants

Citer

Arnaud Chevalier, Julie Hardouin, Pierre-Yves Renard, Anthony Romieu. Universal dark quencher based on "clicked" spectrally distinct azo dyes.. Organic Letters, 2013, 15 (23), pp.6082-6085. ⟨10.1021/ol402972y⟩. ⟨hal-00996556⟩
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