This paper documents the interaction processes between mesoscale convective systems (MCS), the Tropical Easterly Jet (TEJ) and the African Easterly Jet (AEJ) over West Africa during the monsoon peak of 2006 observed during the AMMA project (African Monsoon Multidisciplinary Analyses). The results highlight the importance of the cloud system localization relative to the jets in order to explain their duration and life cycle. A systematical study reveals that intense and long-lived MCSs correspond to a particular pattern where clouds associated with deep convection are located in entrance regions of TEJ, and in exit regions of AEJ. A case study on a particularly well documented convective event characterizes this link and infers the importance of jet streaks in promoting areas of divergence, favoring the persistence of MCSs.