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Article Dans Une Revue Medical Image Analysis Année : 2014

A 3-D spatio-temporal deconvolution approach for MR perfusion in the brain

C. Frindel
D. Rousseau

Résumé

We propose an original spatio-temporal deconvolution approach for perfusion-weighted MRI applied to cerebral ischemia. The regularization of the underlying inverse problem is achieved with spatio-temporal priors and the resulting optimization problem is solved by half-quadratic minimization. Our approach offers strong convergence guarantees, including when the spatial priors are non-convex. Moreover, experiments on synthetic data and on real data collected from subjects with ischemic stroke show significant performance improvements over the standard approaches--namely, temporal deconvolution based on either truncated singular-value decomposition or ℓ2-regularization--in terms of various performance measures.
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Dates et versions

hal-00977610 , version 1 (11-04-2014)

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C. Frindel, M. Robini, D. Rousseau. A 3-D spatio-temporal deconvolution approach for MR perfusion in the brain. Medical Image Analysis, 2014, 18 (1), pp.144-160. ⟨10.1016/j.media.2013.10.004⟩. ⟨hal-00977610⟩
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