Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group. - Archive ouverte HAL Access content directly
Journal Articles Vaccine Year : 2013

Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group.

Catherine Satzke
  • Function : Author
Anni Virolainen-Julkunen
  • Function : Author
Peter V Adrian
  • Function : Author
Kim M Hare
  • Function : Author
Ana Maria Henao-Restrepo
  • Function : Author
Amanda J Leach
  • Function : Author
Keith P Klugman
  • Function : Author
Barbara D Porter
  • Function : Author
Raquel Sá-Leão
  • Function : Author
J Anthony Scott
  • Function : Author
Hanna Nohynek
  • Function : Author
Katherine L O'Brien
  • Function : Author
Non Renseigné
  • Function : Author

Abstract

In 2003 the World Health Organization (WHO) convened a working group and published a set of standard methods for studies measuring nasopharyngeal carriage of Streptococcus pneumoniae (the pneumococcus). The working group recently reconvened under the auspices of the WHO and updated the consensus standard methods. These methods describe the collection, transport and storage of nasopharyngeal samples, as well as provide recommendations for the identification and serotyping of pneumococci using culture and non-culture based approaches. We outline the consensus position of the working group, the evidence supporting this position, areas worthy of future research, and the epidemiological role of carriage studies. Adherence to these methods will reduce variability in the conduct of pneumococcal carriage studies undertaken in the context of pneumococcal vaccine trials, implementation studies, and epidemiology studies more generally so variability in methodology does not confound the interpretation of study findings.

Dates and versions

hal-00972432 , version 1 (03-04-2014)

Identifiers

Cite

Catherine Satzke, Paul Turner, Anni Virolainen-Julkunen, Peter V Adrian, Martin Antonio, et al.. Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group.. Vaccine, 2013, 32 (1), pp.165-79. ⟨10.1016/j.vaccine.2013.08.062⟩. ⟨hal-00972432⟩

Collections

ECOFECT
30 View
0 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More