<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-00917349</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-06T11:23:18+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Collapsin Response Mediator Protein 5 (CRMP5) Induces Mitophagy Thereby Regulating Mitochondrion Numbers in Dendrites.</title>
            <author role="aut">
              <persName>
                <forename type="first">Sébastien</forename>
                <surname>Brot</surname>
              </persName>
              <email type="md5">73e0a1fde444aafee2697b8e1d6e5f3c</email>
              <email type="domain">univ-poitiers.fr</email>
              <idno type="idhal" notation="string">sebastien-brot</idno>
              <idno type="idhal" notation="numeric">182995</idno>
              <idno type="halauthorid" notation="string">20004-182995</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-4373-2135</idno>
              <idno type="IDREF">https://www.idref.fr/168796082</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Carole</forename>
                <surname>Auger</surname>
              </persName>
              <idno type="halauthorid">306579-0</idno>
              <affiliation ref="#struct-1751"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Rabia</forename>
                <surname>Bentata</surname>
              </persName>
              <idno type="halauthorid">785510-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Véronique</forename>
                <surname>Rogemond</surname>
              </persName>
              <email type="md5">a044bfd3c19fa9a73f444007e1c7b617</email>
              <email type="domain">chu-lyon.fr</email>
              <idno type="idhal" notation="numeric">757881</idno>
              <idno type="halauthorid" notation="string">201957-757881</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-2098-920X</idno>
              <affiliation ref="#struct-146197"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Stéphane</forename>
                <surname>Ménigoz</surname>
              </persName>
              <idno type="halauthorid">785511-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Naura</forename>
                <surname>Chounlamountri</surname>
              </persName>
              <idno type="halauthorid">785512-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Agnès</forename>
                <surname>Girard-Egrot</surname>
              </persName>
              <email type="md5">a1d6e693f7d52edef61f08aac4ef5480</email>
              <email type="domain">univ-lyon1.fr</email>
              <idno type="idhal" notation="string">girardegrot</idno>
              <idno type="idhal" notation="numeric">1028391</idno>
              <idno type="halauthorid" notation="string">650073-1028391</idno>
              <affiliation ref="#struct-24487"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jérôme</forename>
                <surname>Honnorat</surname>
              </persName>
              <email type="md5">b4c0c6f91a0140f94d0aecf638f43f43</email>
              <email type="domain">chu-lyon.fr</email>
              <idno type="idhal" notation="string">jerome-honnorat</idno>
              <idno type="idhal" notation="numeric">839407</idno>
              <idno type="halauthorid" notation="string">306582-839407</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-4721-5952</idno>
              <idno type="IDREF">https://www.idref.fr/077852826</idno>
              <affiliation ref="#struct-139719"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Mahnaz</forename>
                <surname>Moradi-Améli</surname>
              </persName>
              <idno type="halauthorid">306583-0</idno>
              <affiliation ref="#struct-33560"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Frédérique</forename>
                <surname>Depierre</surname>
              </persName>
              <email type="md5">cd1dfdcc88b84562f8ec1f0e12883bcd</email>
              <email type="domain">univ-lyon1.fr.invalid</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2013-12-11 16:44:15</date>
              <date type="whenModified">2026-04-23 14:50:04</date>
              <date type="whenReleased">2013-12-11 16:44:15</date>
              <date type="whenProduced">2013-12-09</date>
              <ref type="externalLink" target="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900971"/>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="107870">
                <persName>
                  <forename>Frédérique</forename>
                  <surname>Depierre</surname>
                </persName>
                <email type="md5">cd1dfdcc88b84562f8ec1f0e12883bcd</email>
                <email type="domain">univ-lyon1.fr.invalid</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-00917349</idno>
            <idno type="halUri">https://hal.science/hal-00917349</idno>
            <idno type="halBibtex">brot:hal-00917349</idno>
            <idno type="halRefHtml">&lt;i&gt;Journal of Biological Chemistry&lt;/i&gt;, 2013, 289, pp.2261-2276. &lt;a target="_blank" href="https://dx.doi.org/10.1074/jbc.M113.490862"&gt;&amp;#x27E8;10.1074/jbc.M113.490862&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Journal of Biological Chemistry, 2013, 289, pp.2261-2276. &amp;#x27E8;10.1074/jbc.M113.490862&amp;#x27E9;</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="UNIV-ST-ETIENNE">Université Jean Monnet - Saint-Etienne</idno>
            <idno type="stamp" n="HCL">Hospices Civils de Lyon</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-LYON1">Université Claude Bernard - Lyon I</idno>
            <idno type="stamp" n="INSA-LYON">Institut National des Sciences Appliquées de Lyon</idno>
            <idno type="stamp" n="IFNL">Institut Fédératif des Neurosciences de Lyon</idno>
            <idno type="stamp" n="INC-CNRS">Institut de Chimie du CNRS</idno>
            <idno type="stamp" n="ICBMS" corresp="UNIV-LYON1"> Institut de Chimie et Biochimie Moléculaires et Supramoléculaires</idno>
            <idno type="stamp" n="INSA-GROUPE">Groupe INSA</idno>
            <idno type="stamp" n="UDL">UDL</idno>
            <idno type="stamp" n="UNIV-LYON">Université de Lyon</idno>
            <idno type="stamp" n="CRNL">Centre de Recherche en Neurosciences de Lyon - Lyon Neuroscience Research Centre</idno>
            <idno type="stamp" n="TEST2-HALCNRS">TEST2-HALCNRS</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Collapsin Response Mediator Protein 5 (CRMP5) Induces Mitophagy Thereby Regulating Mitochondrion Numbers in Dendrites.</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Sébastien</forename>
                    <surname>Brot</surname>
                  </persName>
                  <email type="md5">73e0a1fde444aafee2697b8e1d6e5f3c</email>
                  <email type="domain">univ-poitiers.fr</email>
                  <idno type="idhal" notation="string">sebastien-brot</idno>
                  <idno type="idhal" notation="numeric">182995</idno>
                  <idno type="halauthorid" notation="string">20004-182995</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-4373-2135</idno>
                  <idno type="IDREF">https://www.idref.fr/168796082</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Carole</forename>
                    <surname>Auger</surname>
                  </persName>
                  <idno type="halauthorid">306579-0</idno>
                  <affiliation ref="#struct-1751"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Rabia</forename>
                    <surname>Bentata</surname>
                  </persName>
                  <idno type="halauthorid">785510-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Véronique</forename>
                    <surname>Rogemond</surname>
                  </persName>
                  <email type="md5">a044bfd3c19fa9a73f444007e1c7b617</email>
                  <email type="domain">chu-lyon.fr</email>
                  <idno type="idhal" notation="numeric">757881</idno>
                  <idno type="halauthorid" notation="string">201957-757881</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-2098-920X</idno>
                  <affiliation ref="#struct-146197"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Stéphane</forename>
                    <surname>Ménigoz</surname>
                  </persName>
                  <idno type="halauthorid">785511-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Naura</forename>
                    <surname>Chounlamountri</surname>
                  </persName>
                  <idno type="halauthorid">785512-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Agnès</forename>
                    <surname>Girard-Egrot</surname>
                  </persName>
                  <email type="md5">a1d6e693f7d52edef61f08aac4ef5480</email>
                  <email type="domain">univ-lyon1.fr</email>
                  <idno type="idhal" notation="string">girardegrot</idno>
                  <idno type="idhal" notation="numeric">1028391</idno>
                  <idno type="halauthorid" notation="string">650073-1028391</idno>
                  <affiliation ref="#struct-24487"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jérôme</forename>
                    <surname>Honnorat</surname>
                  </persName>
                  <email type="md5">b4c0c6f91a0140f94d0aecf638f43f43</email>
                  <email type="domain">chu-lyon.fr</email>
                  <idno type="idhal" notation="string">jerome-honnorat</idno>
                  <idno type="idhal" notation="numeric">839407</idno>
                  <idno type="halauthorid" notation="string">306582-839407</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-4721-5952</idno>
                  <idno type="IDREF">https://www.idref.fr/077852826</idno>
                  <affiliation ref="#struct-139719"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Mahnaz</forename>
                    <surname>Moradi-Améli</surname>
                  </persName>
                  <idno type="halauthorid">306583-0</idno>
                  <affiliation ref="#struct-33560"/>
                </author>
              </analytic>
              <monogr>
                <idno type="localRef">GEMBAS - Génie Enzymatique</idno>
                <idno type="localRef">Membrane Biomimétique et Assemblages Supramoléculaires</idno>
                <idno type="halJournalId" status="VALID">5882</idno>
                <idno type="issn">0021-9258</idno>
                <idno type="eissn">1083-351X</idno>
                <title level="j">Journal of Biological Chemistry</title>
                <imprint>
                  <publisher>American Society for Biochemistry and Molecular Biology</publisher>
                  <biblScope unit="volume">289</biblScope>
                  <biblScope unit="pp">2261-2276</biblScope>
                  <date type="datePub">2013-12-09</date>
                  <date type="dateEpub">2013-12-09</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1074/jbc.M113.490862</idno>
              <idno type="pubmed">24324268</idno>
              <idno type="pubmedcentral">PMC3900971</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <classCode scheme="halDomain" n="sdv.bbm.bc">Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM]</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>: Degradation of damaged mitochondria by mitophagy is an essential process to ensure cell homeostasis. Because neurons, with a high-energy demand, are particularly dependent on the mitochondrial dynamics, mitophagy represents a key mechanism ensuring a correct neuronal function. Collapsin response mediator proteins 5 (CRMP5) belongs to a family of cytosolic proteins involved in axon guidance and neurite outgrowth signaling during neural development. CRMP5, highly expressed during brain development, plays an important role in the regulation of neuronal polarity by inhibiting dendrite outgrowth at early developmental stages. Here, we demonstrate that CRMP5 is present, in vivo, in brain mitochondria, and is targeted to the inner mitochondrial membrane. The mitochondrial localization of CRMP5 induces mitophagy; CRMP5 over-expression triggers a drastic change in mitochondrial morphology, increases the number of lysosomes and double-membrane vesicles termed autophagosomes, and enhances the occurrence of microtubule-associated protein 1 light chain 3 (LC3) at mitochondrial level. Moreover, LC3 lipidated form, LC3-II, triggering autophagy by insertion into autophagosomes, enhances indicating mitophagy initiation. Lysosomal marker translocates at the mitochondrial level suggesting autophagosome-lysosome fusion, and induces the reduction of mitochondrial content via lysosomal degradation. We show that during early developmental stages, the strong expression of endogenous CRMP5, inhibiting dendrite growth, correlates with a decrease of mitochondrial content. On the opposite, the knockdown or the decrease of CRMP5 expression at later stages, both enhances mitochondrion numbers in cultured neurons, suggesting that CRMP5 modulates these numbers. Our study elucidates a novel regulatory mechanism that utilizes CRMP5-induced mitophagy to orchestrate proper dendrite outgrowth and neuronal function.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="regrouplaboratory" xml:id="struct-1751" status="OLD">
          <orgName>IFR des neurosciences de Lyon</orgName>
          <orgName type="acronym">IFNL</orgName>
          <date type="end">2010-12-31</date>
          <desc>
            <address>
              <addrLine>IFR19 - Bât B13 RdJ 59 Boulevard Pinel 69394 LYON CEDEX 03</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://ifnl.univ-lyon1.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-194495" type="direct"/>
            <relation active="#struct-301088" type="indirect"/>
            <relation active="#struct-300074" type="direct"/>
            <relation active="#struct-300614" type="direct"/>
            <relation name="IFR19" active="#struct-303623" type="direct"/>
            <relation name="IFR19" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-146197" status="VALID">
          <orgName>Centre de Référence Maladie Rare "Syndromes neurologiques Paranéoplasiques"</orgName>
          <desc>
            <address>
              <addrLine>Service de neurologie B CHU de Lyon-GH Est - Hôpital Pierre Wertheimer 59 boulevard Pinel 69677 BRON CEDEX</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300074" type="direct"/>
            <relation active="#struct-308407" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-24487" status="VALID">
          <idno type="IdRef">149115806</idno>
          <idno type="ISNI">0000000122475857</idno>
          <idno type="RNSR">200711911W</idno>
          <idno type="ROR">https://ror.org/00gj33s30</idno>
          <orgName>Institut de Chimie et Biochimie Moléculaires et Supramoléculaires</orgName>
          <orgName type="acronym">ICBMS</orgName>
          <date type="start">2006-01-01</date>
          <desc>
            <address>
              <addrLine>ICBMS UMR 5246 CNRS, Université de Lyon, Université Lyon 1, CNRS, INSA Lyon, CPE Lyon, bâtiment Lederer, 1 rue Victor Grignard, 69622 Villeurbanne Cedex, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.icbms.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-194495" type="direct"/>
            <relation active="#struct-301088" type="indirect"/>
            <relation active="#struct-210962" type="direct"/>
            <relation active="#struct-219748" type="direct"/>
            <relation active="#struct-301232" type="indirect"/>
            <relation active="#struct-341038" type="direct"/>
            <relation name="UMR5246" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-139719" status="VALID">
          <idno type="IdRef">151716412</idno>
          <idno type="ISNI">0000000406147222</idno>
          <idno type="RNSR">201119399T</idno>
          <idno type="ROR">https://ror.org/00pdd0432</idno>
          <orgName>Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center</orgName>
          <orgName type="acronym">CRNL</orgName>
          <date type="start">2011-01-01</date>
          <desc>
            <address>
              <addrLine>Centre Hospitalier Le Vinatier, Bâtiment 462 Neurocampus Michel Jouvet, 95 boulevard Pinel, 69500 Bron</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.crnl.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-194495" type="direct"/>
            <relation active="#struct-301088" type="direct"/>
            <relation active="#struct-300284" type="direct"/>
            <relation active="#struct-1327915" type="indirect"/>
            <relation name="U1028" active="#struct-303623" type="direct"/>
            <relation name="UMR5292" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-33560" status="OLD">
          <orgName>Neuro-oncologie et neuro-inflammation</orgName>
          <desc>
            <address>
              <addrLine>Faculté de médecine Laennec rue G. Paradin 69372 Lyon CEDEX 08</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-194495" type="direct"/>
            <relation active="#struct-301088" type="indirect"/>
            <relation name="U842" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-194495" status="VALID">
          <idno type="IdRef">026402823</idno>
          <idno type="ISNI">0000000121686185</idno>
          <idno type="ROR">https://ror.org/029brtt94</idno>
          <orgName>Université Claude Bernard Lyon 1</orgName>
          <orgName type="acronym">UCBL</orgName>
          <desc>
            <address>
              <addrLine>43, boulevard du 11 novembre 1918, 69622 Villeurbanne cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-lyon1.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301088" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-301088" status="VALID">
          <idno type="ROR">https://ror.org/01rk35k63</idno>
          <orgName>Université de Lyon</orgName>
          <desc>
            <address>
              <addrLine>92 rue Pasteur - CS 30122, 69361 Lyon Cedex 07</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.universite-lyon.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-300074" status="VALID">
          <idno type="IdRef">026534657</idno>
          <idno type="ROR">https://ror.org/01502ca60</idno>
          <orgName>Hospices Civils de Lyon</orgName>
          <orgName type="acronym">HCL</orgName>
          <desc>
            <address>
              <addrLine>3 Quai des Célestins69002 Lyon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300614" status="VALID">
          <idno type="ROR">https://ror.org/04c3yce28</idno>
          <orgName>Centre Hospitalier le Vinatier [Bron]</orgName>
          <desc>
            <address>
              <addrLine>BP 30039 - 95 Bd Pinel 69678 Bron cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ch-le-vinatier.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-308407" status="INCOMING">
          <orgName>Hopital Neurologique</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-210962" status="VALID">
          <orgName>École Supérieure de Chimie Physique Électronique de Lyon</orgName>
          <orgName type="acronym">CPE</orgName>
          <desc>
            <address>
              <addrLine>Domaine Scientifique de la DouaBâtiment Hubert Curien 43 Boulevard du 11 Novembre 191869616 Villeurbanne</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.cpe.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-219748" status="VALID">
          <idno type="IdRef">052444724</idno>
          <idno type="ISNI">0000 0001 2292 0228</idno>
          <orgName>Institut National des Sciences Appliquées de Lyon</orgName>
          <orgName type="acronym">INSA Lyon</orgName>
          <date type="start">1957-03-18</date>
          <desc>
            <address>
              <addrLine>20 Avenue Albert Einstein, 69621 Villeurbanne cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.insa-lyon.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301088" type="direct"/>
            <relation active="#struct-301232" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-301232" status="VALID">
          <idno type="IdRef">162105150</idno>
          <orgName>Institut National des Sciences Appliquées</orgName>
          <orgName type="acronym">INSA</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-341038" status="VALID">
          <idno type="IdRef">232435103</idno>
          <idno type="ISNI">000000010626358X</idno>
          <idno type="ROR">https://ror.org/02cte4b68</idno>
          <orgName>Institut de Chimie - CNRS Chimie</orgName>
          <orgName type="acronym">INC-CNRS</orgName>
          <date type="start">2009-10-01</date>
          <desc>
            <address>
              <addrLine>CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE3 rue Michel-Ange75794 PARIS CEDEX 16 - France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.cnrs.fr/inc</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300284" status="VALID">
          <idno type="IdRef">028209966</idno>
          <idno type="ISNI">0000 0001 2158 1682</idno>
          <idno type="ROR">https://ror.org/04yznqr36</idno>
          <idno type="Wikidata">Q623154</idno>
          <orgName>Université Jean Monnet - Saint-Étienne</orgName>
          <orgName type="acronym">UJM</orgName>
          <date type="start">1969-03-27</date>
          <date type="end">2025-01-01</date>
          <desc>
            <address>
              <addrLine>10, Rue Tréfilerie – CS 8230142023 Saint-Étienne Cedex 2</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-st-etienne.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1327915" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-1327915" status="VALID">
          <idno type="IdRef">285395831</idno>
          <orgName>Université Jean Monnet (EPSCPE)</orgName>
          <orgName type="acronym">UJM EPE</orgName>
          <date type="start">2025-01-01</date>
          <desc>
            <address>
              <addrLine>10 rue Tréfilerie42100 Saint-Etienne</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-st-etienne.fr/fr/index.html</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>