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Communication Dans Un Congrès Année : 2012

PROGRESS ON MULTISCALE REPRESENTATION OF CARDIAC VALVE MORPHOGENESIS.

Résumé

Executable biology at various levels of spatial scale is becoming increasingly important in order to understand the complexity exhibited in living systems. This paper describes how a multiscale systems approach can be used to integrate these models of behaviour to provide an insight into the development of cardiac valves. In particular, simulations of epithelial to mesenchymal transition using a Cellular Potts model are shown to demonstrate cell adhesion and imitate faithfully the in vivo process. As a consequence, this work also shows the importance of measurement of surface energy of adjacent cells and its effect on systemic behaviour.
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Dates et versions

hal-00906730 , version 1 (20-11-2013)

Identifiants

  • HAL Id : hal-00906730 , version 1

Citer

R. Summers, T. Abdulla, Jean-Marc Schleich. PROGRESS ON MULTISCALE REPRESENTATION OF CARDIAC VALVE MORPHOGENESIS.. Metrology for Green Growth, Sep 2012, Busan, South Korea. pp.1-4. ⟨hal-00906730⟩
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