Quantification of within- and between-pen transmission of Foot-and-Mouth disease virus in pigs - Archive ouverte HAL Access content directly
Journal Articles Veterinary Research Year : 2006

Quantification of within- and between-pen transmission of Foot-and-Mouth disease virus in pigs

Phaedra Eblé
  • Function : Author
Aline de Koeijer
  • Function : Author
Annemarie Bouma
  • Function : Author
Arjan Stegeman
  • Function : Author
Aldo Dekker
  • Function : Author

Abstract

Quantified transmission parameters of Foot-and-Mouth Disease Virus (FMDV) are needed for epidemic models used for control and surveillance. In this study, we quantified the within- and between-pen transmission of FMDV in groups of pigs by estimating the daily transmission rate $\beta $, i.e. the number of secondary infections caused by one infectious pig during one day, using an SIR (susceptible-infectious-removed) model. Within-pen transmission was studied in four groups of ten pigs in which 5 infected and 5 susceptible pigs had direct contact; between-pen transmission was studied in one group of ten pigs in which 5 infected and 5 susceptible pigs had indirect contact. Daily results of virus isolation of oropharyngeal fluid were used to quantify the transmission rate $\beta $, using Generalised Linear Modelling (GLM) and a maximum likelihood method. In addition, we estimated the expected time to infection of the first pig within a pen $T_{w}$ and in the indirect-contact pen $T_{b}$. The between-pen transmission rate $\beta $$_{b}$ was estimated to be 0.59 (0.083-4.18) per day, which was significantly lower than the within-pen transmission rate $\beta $$_{w}$ of 6.14 (3.75-10.06). $T_{w}$ was 1.6 h, and $T_{b}$ was 16 h. Our results show that the transmission rate is influenced by contact structure between pigs.
Fichier principal
Vignette du fichier
hal-00903048.pdf (109.95 Ko) Télécharger le fichier
Origin : Explicit agreement for this submission
Loading...

Dates and versions

hal-00903048 , version 1 (01-01-2006)

Identifiers

Cite

Phaedra Eblé, Aline de Koeijer, Annemarie Bouma, Arjan Stegeman, Aldo Dekker. Quantification of within- and between-pen transmission of Foot-and-Mouth disease virus in pigs. Veterinary Research, 2006, 37 (5), pp.647-654. ⟨10.1051/vetres:2006026⟩. ⟨hal-00903048⟩
33 View
111 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More