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Article Dans Une Revue Veterinary Research Année : 2007

Feline herpesvirus

Rosalind Gaskell
  • Fonction : Auteur
Susan Dawson
  • Fonction : Auteur
Alan Radford
  • Fonction : Auteur
Etienne Thiry
  • Fonction : Auteur

Résumé

Feline herpesvirus (FHV-1; felid herpesvirus 1 (FeHV-1)) is an alphaherpesvirus of cats closely related to canine herpesvirus-1 and phocine herpesvirus-1. There is only one serotype of the virus and it is relatively homogenous genetically. FeHV-1 is an important cause of acute upper respiratory tract and ocular disease in cats. In addition, its role in more chronic ocular disease and skin lesions is increasingly being recognised. Epidemiologically, FeHV-1 behaves as a typical alphaherpesvirus whereby clinically recovered cats become latently infected carriers which undergo periodic episodes of virus reactivation, particularly after a stress. The primary site of latency is the trigeminal ganglion. Conventional inactivated and modified-live vaccines are available and protect reasonably well against disease but not infection, although viral shedding may be reduced. Genetically engineered vaccines have also been developed, both for FeHV-1 and as vector vaccines for other pathogens, but none is as yet marketed.
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Dates et versions

hal-00902876 , version 1 (11-05-2020)

Identifiants

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Rosalind Gaskell, Susan Dawson, Alan Radford, Etienne Thiry. Feline herpesvirus. Veterinary Research, 2007, 38 (2), pp.337-354. ⟨10.1051/vetres:2006063⟩. ⟨hal-00902876⟩
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