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Article Dans Une Revue Environmental Health Perspectives Année : 2012

European birth cohorts for environmental health research.

1 IMIM-Hospital del Mar
2 CREAL - Center for Research in Environmental Epidemiology
3 Spanish Consortium for Research on Epidemiology and Public Health
4 Institute of Environmental Medicine
5 School of Social and Community Medicine
6 GERHM - Groupe d'Etude de la Reproduction Chez l'Homme et les Mammiferes
7 Division of Epidemiology
8 Department of Dermatology and Allergy Centre
9 Department of Public Health
10 Risk Assessment Sciences Institute
11 VDU - Vytautas Magnus University - Vytauto Didziojo Universitetas
12 Institute of Social Medicine
13 Department of Environmental Health
14 Environmental Risk and Health Unit
15 IUF
16 ISPM - Institute of Social and Preventive Medicine
17 Epidemiology and Preventive Medicine
18 Section of Social Medicine
19 Department of Social Medicine
20 Department of Occupational Medicine and Public Health
21 Department of Urban Environment
22 Department of Environmental Epidemiology
23 Department of Epidemiology
24 Cancer Epidemiology Unit
25 Department of Hygiene and Epidemiology
26 Environmental Epidemiology Applied to Reproduction and Respiratory Health
27 Institute of Experimental Medicine AS CR
28 Department of Epidemiology
29 EPI - Institute of Epidemiology [Neuherberg]
30 Department of Occupational Medicine
31 SMU - Slovak Medical University of Bratislava
32 INVS - Institut de Veille Sanitaire
33 Department of Public Health
34 Hygiene, Social and Environmental Medicine
35 BIHR - Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
Ulrike Gehring
Ursula Krämer
  • Fonction : Auteur
IUF

Résumé

BACKGROUND: Many pregnancy and birth cohort studies investigate the health effects of early-life environmental contaminant exposure. An overview of existing studies and their data is needed to improve collaboration, harmonization, and future project planning. OBJECTIVES: Our goal was to create a comprehensive overview of European birth cohorts with environmental exposure data. METHODS: Birth cohort studies were included if they a) collected data on at least one environmental exposure, b) started enrollment during pregnancy or at birth, c) included at least one follow-up point after birth, d) included at least 200 mother-child pairs, and e) were based in a European country. A questionnaire collected information on basic protocol details and exposure and health outcome assessments, including specific contaminants, methods and samples, timing, and number of subjects. A full inventory can be searched on www.birthcohortsenrieco.net. RESULTS: Questionnaires were completed by 37 cohort studies of > 350,000 mother-child pairs in 19 European countries. Only three cohorts did not participate. All cohorts collected biological specimens of children or parents. Many cohorts collected information on passive smoking (n = 36), maternal occupation (n = 33), outdoor air pollution (n = 27), and allergens/biological organisms (n = 27). Fewer cohorts (n = 12-19) collected information on water contamination, ionizing or nonionizing radiation exposures, noise, metals, persistent organic pollutants, or other pollutants. All cohorts have information on birth outcomes; nearly all on asthma, allergies, childhood growth and obesity; and 26 collected information on child neurodevelopment. CONCLUSION: Combining forces in this field will yield more efficient and conclusive studies and ultimately improve causal inference. This impressive resource of existing birth cohort data could form the basis for longer-term and worldwide coordination of research on environment and child health.
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Dates et versions

hal-00875997 , version 1 (24-10-2013)

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Martine Vrijheid, Maribel Casas, Anna Bergström, Amanda Carmichael, Sylvaine Cordier, et al.. European birth cohorts for environmental health research.. Environmental Health Perspectives, 2012, 120 (1), pp.29-37. ⟨10.1289/ehp.1103823⟩. ⟨hal-00875997⟩
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